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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3788d163a6f3b4e15e9f5fb05a9eeac30aa47db7d21971129cf9bcf68f0e66e9' 
  AND token = 'YNse1hOvnw4Cgj7Rbe3I51cWCfz5Tsl4sB0NyrSIEsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}