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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41185cc36ab50b00eb40ac86a5fca1883cd216bf75a17ca298c4b6e9d09f6794' 
  AND token = 't2Jjyta92hiNwJ4EqYetDc30tnCCqxMYwYgQmtrKoNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}