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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a03623f370afcbfc8dc2e1378546e6084986cac644ac0560899c14f8153f52ca' 
  AND token = 'giVnumww9Q36hujdY3twICxYFCyaRxqTRPHA0XJTNUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}