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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f67d7b277dddefe8e858d7939becf55199b6571a8b3c0f33ab340b898cb8445' 
  AND token = 'qMZR8Vt+IeiwQtONook2E1OuGOdcjtiVtrk6Trdu60c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}