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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9ce6e08b0746332c25104b82dae661ecd91773e441739b2056a5e9a22c9c0a' 
  AND token = '0OenkW+6xhuRB6IOFyTVmJQTZvF78Wh3g0d/db4T67Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}