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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290d677e96606832897cee2c8f4dcf3bf7f88286c8f24bf7ceb83e51e39b7f5c' 
  AND token = 'd7HzB3qKVrMS7YglNEafSCO0K8NkmjSpaDMVtx4ZDQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}