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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ace7b0ccbf1bb47bcfbddb079550692e6818b7e5d2775f5e9dc4c75750fc14f' 
  AND token = 'yUCFyO4H4wwszPXzPp2a8j4Py1aqCfOUvUhfL187IQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}