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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c537485c69a1b49e71ec1e5158e3f0626c4e17a02676364f53d39968dfea3089' 
  AND token = 'yh325GJ5uJ8rR4Ep7mSlnlwgXAbMaQvKxE410OM0ttc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}