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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66c3c1cc8042089d0b134fe7f2bb1a1b9768e2ebd978a8e05f72fad3159261cc' 
  AND token = 'vAabS4Xdu6fJXOgC2Ro3KDKtsfeStxxB5AWfHGfUNzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}