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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ac59d2c9410848f177a426a290d61e6bb97bf516977da3104850a8712069ffa' 
  AND token = 'xiXBZmzRcJ2cz3eYSzOsevoo+pDkaxAhmRss2mU6ZvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}