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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c4ed260a6333d1b0f4df609900a26c99123aab8815f01eeaca8f0e2831e999c' 
  AND token = 'aGY653DLFyLiDogKtTMkqVIm0WXcImkTDdoSY9sX4x8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}