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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d23361cb9f333089dbcc695c89b1813c2503d1bf232c6d8f63daed65af0741' 
  AND token = 'hwlsU4vzsv8JUhYu38BsvDPXEXuSgm/LeYDlryStw2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}