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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebb678cedbe7686958466e22e70368c00d759565b58773b0c2b5d96948d7ad0f' 
  AND token = 'RFiPF5v0bTd/dTuMyU954BYLV5BBrCM/3eo3zNrCBIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}