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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0738050cbf4bca631b67494c6035c8c11e7002bcbe292b4ad72c86ae05f1db8b' 
  AND token = 'HsPgIcmVVf/v4aTpF6gKTHHfjnP0LcYmDSlTsjsH3Bg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}