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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81b5eb7c2b1269018fb79de0caa4f8dead6a7e540a01cc0c36cc541aaa3688c5' 
  AND token = 'xw9/g5FOPEu2qdUGksYVj5o0dbkQiRz7o6SLiJjWnmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}