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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c24405fb880c7ff112d4d58f302851452e64deb6a0aa8a2602fbd1844b7f5b' 
  AND token = 'JOy946YYz/OScIh589txFKxBbD5w3LzNO0EsBQfRHoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}