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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42fc07a6a09c27890915b17aa97574877c424147815155d3e451a3564a507c89' 
  AND token = '0b36NMn208ReGoeGstLI/+2pmlu9JgkSmqCNYiYs3yI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}