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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b9823f811f67d722d3f1fd168fa74ba6f427036c9bbb475364bb49f28b46b8' 
  AND token = '/fFol2TCqIu+HxbZrfpvheXg1m4BAfuQ9+TH69+05Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}