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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b803dd0215a46d03652a24a13a844b43efa4c34b8779b9f2de3b5215440dc39' 
  AND token = 'kTJ0Pms+1dW8VGiwHqyabC4QK2vnMwF7r51J97je6xc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}