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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb58aac393f4221a3e3394f67b2d6b85c6dbdad56547de20fc876805abc68726' 
  AND token = 'kgqD6Q3k7B7YFhXHMAmYV7iRxH56iQmgR52uzlfoOdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}