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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6deb554c7bb0285c3d901f6bbb3c04a4e745a1d9517fc5946b9a8b9417698c81' 
  AND token = 'oQoeAvwLUtts5mu9NwjqJN+WW05LX1po5fDFzrAqB1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}