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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8365bcac14e921f0fd6fb622e1a86e177b1677aa30de24a49673bb0f10be0151' 
  AND token = 'NH2N4DsQkJk2LKSzTq+gx6dftoyk/ceBRFLu9VeUNkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}