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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8836f0142b9998667d8088658649a6075dee0d98bb6e6648cf1230b0311f5d06' 
  AND token = 'll1YLQLxMiusjR0M5f6hMBS333PBglW+AndxK55aBRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}