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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6a460fc3676051a3310bd8d9ac31f94da0e356ad5a43e87fead7554b25f2a66' 
  AND token = 'Yxl1o/fVXGbQOU1o0Z8KkdmyJQbEoEd7gMe93B6SICM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}