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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29d1e3d47aad1298e5fb3b32886f5b1175aa4d37d4f93a8da5bdee9d449d7d89' 
  AND token = 'nvCxCgJQLRm9e8pRM76kfZe2NSC4ThCL+CwiBuWjbIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}