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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c3a0abf70a9e12b25b980100ab0859a79cd49e5a642215fe33fee2948696ddf' 
  AND token = 'Q8Y1Y/JTDPMZg07BnaRTQQCTQVb0un/Pc26iSW0dsV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}