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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b9633828034de6a105d2690998b153bc8c9612fc1fb3fdf9ce05eaf32a734ae' 
  AND token = 'V6lb+kaV+bDeznOMwpElFpevo0QPZRwBZbmGEc2TF/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}