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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '561b0bbd547bbec066cb36e36a1331e83fe3be4eb383c7658bf96a5f7368f41a' 
  AND token = 'Nw4Bu0XUd8QSVGLFEX8zLcgCIaplfl82etedky6Am8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}