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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac9cf2f63e9e5217815958c0fae1288bfd727584c24db79c05c87dfa438f152' 
  AND token = 'AthSE54x0X93ZhGVTLV7+PDKZBjVmL7HRP77df+6qqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}