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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4be21f81730cd6969409116084d115f7722986d221e5bcd1e05bd29c27ab7fdf' 
  AND token = 'n53YxMj5rjmr4N9B73RnEnShbLVXo8YmFFVC79oaCGk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}