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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7e26a5c5a60b80ede3003c2a0c5912054b2c7d9780caa014d8da868e222e0ef' 
  AND token = 'roKWeafct6jNUK8kAG4jfiYHX6UWAhPqH+g2d1DZ8fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}