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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '795c9ce4fbb7d68f4181ae247c78a26971ae619835d496bc5670ff0bd5025087' 
  AND token = 'NVcjc1gWCNQw2ELqAwGD0q534G0WXydXx+lQeMuKxdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}