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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d0e4d37e35f0473e4b3dbd50e686cef49febc329cdb7ecf2108412f185c79e9' 
  AND token = 'fpymmna1fIwjze4nPL7gvUV8iDRhMHu66to5aT6lWHI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}