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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e0e8a4018d68aa2f10fc298a8f0d24dffce0be9cc21f4c157d9fab8b9847997' 
  AND token = 'WAsRAV2uGE5hJ2bhR9fMn49LaxcJFT/H8GJbveGmQIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}