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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3408a29ab7889c89474d2246d2b920e0768b0ff588a15eb30a72fe593291f1fc' 
  AND token = 'sgHMiXJvrWef/ETkBhwvHrYfbOkIVwnYnvU9Dbn59P8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}