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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '31280e1af0a9df81414e3c90126576adbbb696066a8b7701a0b5ae19750b82f1' 
  AND token = 'RM4ohtZ3/XMjYXwA03dT5f5WwgM5cUKWgzAOxiJomw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}