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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5303838cb7889eb462b160d11528926e8e659582b82e7041a769e216c309961a' 
  AND token = '5vOkC0ZtfZONnanBK/JAxvwNwp6BOmLnNWaGTItf2RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}