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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ada00c34499ac92a8a1a1fa0e3e2541dd780c50178a513168e45f79a0e091e87' 
  AND token = 'OeYq1pPSvTorgZgBpSN6oy61vp+K30gNxbr9AEZMbeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}