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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69b843f0f16ce4660c1a9150031db86cb50c42668eb1d363f4058c2c302d8b99' 
  AND token = 'lyO+Wcoo+jhXOub7zzRy7pWZ6gHf2hCymwnfPHDjmfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}