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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb0254fd41670202095b011aa5c33860819efaf1b64707c60750061e2c49dc42' 
  AND token = 'pW61DGV1GOueoTo4MTcCqNIpf6MnqFRKguOYCbsZOkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}