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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57ffbf177ea766a06dc60d52c1e964eda1d8ff760fa624773f9e178b5c664baa' 
  AND token = 'L7Z2tu7LWaQL3130HTtvWictpaAllYGjTpDM1R7wj3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}