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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36ae5db954cb88a09090bd5ad6c81ef0b306a5d55fae03d7cc5dcb558f2b3975' 
  AND token = 'UIQweEL65oLLtPAL2/Zx1j/J/Mow3uZwqlFSfbGXd0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}