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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25f3663481d58655138d9e6f625921452d002879bf5ac97070f61e05b09e8205' 
  AND token = '8PSYeCRDlT6OFAURBNVidbie/Z+gXdZu9ijOZcoFlZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}