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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd354c1277c93183535afe979c72a4fba9a4a5ff11712f9e5c0c77d70014f96c5' 
  AND token = 'aYbCkmTw06nIfIwQKyyy16wtmjw6LwrBE1WcbXKjhDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}