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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9f75a5d8bb0e494acf05cd7bfa97d51c3d493770fdbaa4aedb5184cd0dd1c5' 
  AND token = 'DMwH5VGmQh/xcx3sudBZ8oo1aitQ7TsYsvW88BeXKg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}