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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c002847613f991c9f7dd9308b9cfeb23141659b94b9add6a886773422d3cea8' 
  AND token = 'NN+yl6ucUKp0WN08EcM9Ra41gmRL3Fd4hGkzD1GnsRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}