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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '067dacedc0b3dee6085abb854b3dedb449f674cf1b0fd7ef7061d1a38d3a0401' 
  AND token = 'CLfpPy0CGDSVCkasJFI3919+Ce7PQeglLHZu6gBsPLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}