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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f52a0836fdc5b6a00cfbe5dd37437fba1da46ca82a90b48862512a0eea00aa38' 
  AND token = 'I2z6/Ag9PHJFhAi/oNb+HlVS05Ga1fdm85/malVfCLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}