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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5876c3726538ea3a8bc504d82089012d124c026199b8c29bce80e6b3768ae143' 
  AND token = 'b1bGtxLHQLhgZLOIZ0vvJHAb34i/pnZJ7NM2rYAcH5U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}