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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '652e099c375b09b047b9fb71d73d9f6ead79a6d0e032e641f1ad2133ee57df60' 
  AND token = 'on+lMnlEOqOoWWOFI7YqR0vt+g1AtCu+LQuRkoNryJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}